Manufacturing highly toxic compounds in a biopharmaceutical environment tests equipment and systems. The global market for highly potent active pharmaceutical ingredients (HPAPIs) has been growing ...

This article discusses a number of factors that may influence the behaviour of conjugated biopharmaceuticals. Optimizing bioconjugation processes may be critical to achieve the desired drug ...

The coupling and decoupling of molecular units is a fundamental undertaking of organic chemistry. Herein we report the use of a very simple conjugate acceptor, derived from Meldrum's acid, for the ...