One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

HOUSTON – (Aug. 9, 2022) – Knowing the structure of a complex biological system isn’t nearly enough to understand how it works. It helps to know how the system moves. In that light, Rice University ...

In recent months I’ve highlighted two excellent iPad apps by OnScreen Science that center around a 3D model of DNA. For the sake of completeness, let me now mention the third and final member of the ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...

Reactive oxygen species (ROS) were long regarded as harmful by-products of mitochondrial metabolism, but growing evidence—including our own—shows that ROS also signal to core processes such as ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...