Manufacturing highly toxic compounds in a biopharmaceutical environment tests equipment and systems. The global market for highly potent active pharmaceutical ingredients (HPAPIs) has been growing ...

The Horner--Wadsworth--Emmons (HWE) reaction is commonly used in organic chemistry to synthesize conjugated aldehydes. However, traditional HWE reaction methods sometimes have inconsistent (E)- and (Z ...

We describe here a convenient procedure for assessing the relative cell permeability of chemical compounds. The assay can be used in a high-throughput mode and is particularly applicable for the ...

The synthesis and isolation of a nitrogen-embedded polycyclic compound with strong antiaromaticity and stability was achieved for the first time by a research group at Ehime University. This result ...

A research group has discovered that the 'non-essential' amino acid taurine is important for protein translation in mitochondria and is involved in mitochondrial disease development. The group also ...

$6 million investment in Cynaptec Pharmaceuticals secured to advance research and early-stage clinical trials for chronic cluster headaches and addiction Option for an additional $20 million ...